معرفی
Keiichiro Susuki, MD, PhD, serves as an Associate Professor in the Department of Neuroscience, Cell Biology, and Physiology at the Boonshoft School of Medicine, Wright State University. His research focuses on molecular mechanisms of myelinated nerve fiber development, maintenance, injury, and repair, with emphasis on the axon initial segment and nodes of Ranvier to address neurological diseases.
His educational background includes:
- MD from Yokohama City University School of Medicine, Japan (1994)
- PhD from Yokohama City University School of Medicine, Japan (2001)
- Postdoctoral training at Baylor College of Medicine, TX (2007-2008)
- Postdoctoral training at University of Connecticut Health Center, CT (2005-2007)
Susuki's research centers on nervous system development and injury, investigating glial cytoskeletons and molecular complexes at critical neural domains. He employs genetically modified mice, nerve injury models, and neuron cultures to study myelin biology, axon physiology, and neural repair mechanisms for conditions like diabetic neuropathy and autoimmune disorders.
His recent publications reveal a strong focus on type 2 diabetes-induced neural dysfunction, particularly methylglyoxal-mediated disruption of axon initial segments and paranodal junctions. Research also explores spectrin/TDP-43 roles in nerve conduction and myelin integrity, with translational implications for diabetic neuropathy and nerve regeneration.
Susuki actively mentors PhD, MD/PhD, MS, and undergraduate students, with trainees securing NIA/NINDS NRSA F30 fellowships and university research grants. His own research is funded by NINDS R01, R03, and R56 grants targeting molecular mechanisms of myelinated nerve fibers.
As part of the Translational Neuroscience Institute, he leads a collaborative laboratory team investigating cytoskeletal dynamics in neural injury and repair, utilizing molecular, cellular, and electrophysiological approaches to develop novel therapeutic strategies.
