معرفی
Ke Zhang Reid is an Associate Professor in the Department of Biology at Wake Forest University. She leads an active research laboratory focusing on epigenetic and genomic regulation in cell biology, utilizing fission yeast and mammalian systems to understand gene expression and disease mechanisms.
Education:
- PhD, Genes & Development program, University of Texas, M.D. Anderson Cancer Center, Houston, Texas (2005)
- Postdoctoral Fellow, Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, NIH, Bethesda, Maryland (2006–2012)
- MS, Oncology, Peking Union Medical College, Beijing, China (1999)
- BS, Biochemistry, Wuhan University, Wuhan, China (1997)
Her research centers on epigenetics, genomics, and cell biology, particularly how non-coding RNAs and histone modifications such as lysine methylation and deacetylation regulate cellular identity and function. She investigates how dysregulation of these mechanisms contributes to diseases like cancer and neurological disorders. Her lab integrates genetic, biochemical, proteomic, and genomic approaches to dissect nuclear signaling networks and epigenome dynamics.
Her recent publications demonstrate a strong focus on chromatin regulation, heterochromatin formation, RNA quality control, and the role of epigenetic mechanisms in drug addiction and cancer. The articles span model systems from fission yeast to mammalian models, reflecting a multidisciplinary and translational approach. Key themes include histone modifications, RNA interference, gene silencing, and transcriptional regulation.
Scientific Awards:
- No awards explicitly mentioned in the text.
Dr. Reid mentors graduate students and offers Ph.D. and MS positions in her lab. While specific grants are not listed, her sustained publication record in top-tier journals suggests active external funding. She maintains a dedicated lab website and has produced outreach materials such as a lab movie, indicating a strong commitment to research communication and training.
Labs and Research Teams:
She leads the Zhang Lab at Wake Forest University, which is actively engaged in epigenetics research using fission yeast and mammalian cells. The lab employs a range of molecular and genomic techniques and collaborates within the broader biology department and beyond.
