Katie Burnham

Katie Burnham is a Researcher at the Wellcome Sanger Institute, affiliated with the Human Genetics Programme. She previously held a Postdoctoral Research Fellowship at the University of Oxford's Knight group and earned her PhD in Clinical Medicine from the Wellcome Centre for Human Genetics, Oxford.

Her research focuses on functional genomics and host immune response variations in sepsis, integrating genomic, transcriptomic, and clinical data to identify disease subgroups (endotypes) for precision medicine applications. Key contributions include defining endotype-specific treatment responses in clinical trials like VANISH and uncovering genomic drivers of sepsis heterogeneity.

Notable trends in her peer-reviewed work (2025–2020) include:

• Application of multi-omics integration (genomics, transcriptomics, proteomics) to critical care medicine
• Development of transcriptomic signatures for sepsis stratification and outcome prediction
• Exploration of genetic determinants
• Analysis of immunological archetypes and regulatory networks in acute infections

Her work has been published in journals such as Nature Genetics, Science Translational Medicine, and The Lancet Respiratory Medicine.