Katherine L. Perkins

Katherine L. Perkins, PhD is an Associate Professor in the Department of Physiology and Pharmacology at SUNY Downstate Medical Center, focusing on neurophysiology and epilepsy research. Her work investigates GABAergic signaling, interneuron networks, and extracellular space dynamics in seizure mechanisms.

• Research Themes:
• Depolarizing GABA responses in hippocampal neurons
• Interneuron network activation patterns
• Role of extracellular matrix in epilepsy
• Pharmacological modulation of seizure activity

Key Techniques: Cell-attached and whole-cell patch-clamp recording, rodent brain slice models, synaptic current analysis. Her publications span Journal of Neurophysiology, Epilepsy Research, and Journal of Neuroscience, with a focus on synaptic transmission and neuronal excitability in epilepsy models.

• Collaborations:
• Sabina Hrabetova's lab (extracellular space studies)