Karl-Klaus Conzelmann

Karl-Klaus Conzelmann is a Professor at the Department of Virology, Ludwig-Maximilians-Universität München (LMU). His research focuses on negative-strand RNA viruses like rabies and measles, exploring their interaction with host cell machinery and applications in neuronal tracing and antiviral strategies. He employs reverse genetics and CRISPR-based editing to study virus replication and host-pathogen dynamics.

His work spans virology, molecular biology, and neuroscience. Recent studies include synaptic tracing using rabies virus variants, immune evasion mechanisms in RNA viruses, and neurodegenerative disease modeling. He has contributed to COVID-19 vaccine development and understanding mitochondrial-ER interactions in astrocytes.

Key trends in his publications involve CRISPR applications, innate immune antagonism by viral proteins, and neuronal circuit mapping. His studies often integrate virology with neurobiology, highlighting cross-disciplinary approaches.

Scientific Awards:

• Loeffler-Frosch Prize of the German Society for Virology (1995)
• Ph.D. student fellowship, State of Baden-Württemberg (1985-1987)

Conzelmann's lab has secured funding through DFG (Co260/5), SFB870, and SPP1665. His team collaborates on host-pathogen interaction and neurovirology projects, with a focus on viral genome engineering and interferon signaling.