معرفی
Kariona Grabinska is an Associate Research Scientist in the Department of Cellular & Molecular Physiology at the Yale School of Medicine, part of Yale University. Her work focuses on enzymology, protein glycosylation, and metabolic pathways with a particular emphasis on cis-prenyltransferase complexes and their roles in cellular processes.
She earned her PhD from the Polish Academy of Sciences in 2002. Her research spans structural biology, molecular mechanisms, and genetic disorders, with contributions to understanding yeast genetics and human diseases linked to glycosylation defects. Collaborations include studies on mitochondrial glutathione regulation, TNFα signaling, and vascular development.
Her publications highlight investigations into dolichol biosynthesis, spore wall formation in yeast, and the genetic basis of progressive myoclonus epilepsies. She has also explored interactions between endothelial cells and glucocorticoid receptors, linking them to Wnt signaling pathways. Her work bridges fundamental cellular biology with translational medicine, emphasizing enzyme function and disease mechanisms.
