معرفی
Karen McLuskey is a Research Associate in the Department of Molecular Biosciences at the University of Glasgow, College of Medical, Veterinary and Life Sciences. Her work focuses on structural biology and enzymology within parasitic organisms.
- 2010-2014: Wellcome Trust Grant for structural and activity studies of trypanosomatid metacaspases
Research Interests: McLuskey's research spans structural biology, parasitology, and cysteine peptidase studies, particularly in trypanosomatid pathogens like Leishmania and Trypanosoma. Her publications demonstrate expertise in protein crystallography, enzymatic activity analysis, and membrane protein purification techniques.
Publication Trends: Recent work (2024) examines TORC1 as a nutrient-regulated regulator in Leishmania, while earlier studies focus on metacaspase structures, cysteine peptidases, and high-throughput methodologies for protein analysis. Themes include parasite biology, structural enzymology, and microbiome interactions.
Scientific Contributions:
- Crystal structure determination of key parasitic enzymes
- Development of high-throughput protein purification protocols
- Metabolite activity ranking algorithms
Labs & Collaborations: McLuskey collaborates closely with Jeremy Mottram's research group, focusing on parasitic disease mechanisms and structural characterization of virulence factors.
