معرفی
Kamran Diba, Ph.D., is an Associate Professor in the Department of Anesthesiology at the University of Michigan Medical School. He is an affiliate faculty member in the Neuroscience Graduate Program and the Biomedical Engineering (BME) program. His research focuses on understanding how neuronal networks in the hippocampus generate oscillations and spike patterns that underlie memory formation and retrieval. The Diba Lab employs multi-channel electrophysiological recordings, optogenetics, and advanced computational methods to study neural circuits in freely moving rodents.
Key research interests include the role of theta oscillations (5-12 Hz) and sharp-wave ripples (100-250 Hz) in hippocampal function, the encoding of spatial information via phase precession, and the impact of sleep and anesthesia on neural activity. The lab combines machine learning with experimental techniques to analyze high-dimensional spike train data and perturb neural circuits using optogenetics and chemogenetics.
Recent work highlights the lab's exploration of how sleep loss disrupts hippocampal reactivation, the stabilization of neural networks under optogenetic manipulation, and the development of novel tools like 3D-printed microdrive systems for electrophysiological recordings. Dr. Diba's interdisciplinary approach bridges neuroscience, engineering, and computational modeling to uncover fundamental principles of memory processing.
His lab is located at 3311 Med Sci I, with a primary website at diba-lab.github.io. Ongoing projects investigate synaptic plasticity resilience, hippocampal-prefrontal connectivity, and the dynamics of spike transmission between principal cells and interneurons.
