Jörg Stetefeld

Dr. Jörg Stetefeld is a Professor and Tier 1 Canada Research Chair in Structural Biology and Biophysics at the University of Manitoba's Faculty of Science, Department of Chemistry. His research laboratory is located in Parker Building, room 480, and he can be reached at Jorg.Stetefeld@umanitoba.ca or by phone at 204-474-9731.

Dr. Stetefeld's primary research interests include structural biology, biophysics, and signal transduction, with a focus on understanding the structure-property relationship of protein-protein and protein-ligand interaction networks. His laboratory employs a hybrid method approach combining X-ray crystallography, cryo-3D Electron microscopy, SEC-SAXS, NMR, and various biophysical techniques including SEC-MALS-QUELS, AUC, MST, nano-DSF-DLS, BLI, and iSCAMS. The lab also utilizes advanced molecular dynamics simulations and artificial intelligence programs for in vitro and in vivo functional analysis.

• Tier 1 Canada Research Chair in Structural Biology and Biophysics

Dr. Stetefeld has founded several research centers including the Center for Oil and Gas Research and Development (COGRAD) in 2014 (in collaboration with Dr. Tomy), the Center for Integrated Structural Biophysics (CISB) in 2019, and White Otter Biotech Inc. in 2024, which provides eDNA/eRNA based biodiversity monitoring and environmental modeling approaches for industry and government clients. His laboratory is equipped with state-of-the-art infrastructure including facilities for insect- and mammalian cell expression, HP-Fermenter systems, PCR's, Next Generation Sequencer, crystallization facilities, crystal microspectrophotometer, TALOS F200C electron microscope, X-ray diffractometer, and 600MHz NMR instrumentation.