Jörg Rademann

Prof. Jörg Rademann is a Professor of Pharmaceutical/Medicinal Chemistry at Freie Universität Berlin since 2013. His research group specializes in fragment-based drug discovery and chemical biology, focusing on protein-ligand interactions for disease-related targets in cancer, Alzheimer's, tuberculosis, and viral infections (SARS, Zika, dengue, West Nile). The group integrates synthetic organic chemistry with bioanalytical, biochemical, and biophysical techniques, operating within the Department of Pharmacy at Freie Universität Berlin.

• B.Sc., M.Sc., and Ph.D. teaching: Inorganic and organic drug chemistry, pharmaceutical analysis
• Co-initiator of national ChemBioNet for chemical biology collaboration
• Developed Dynamic Ligation Screening (DLS) for fragment identification

Research Interests include:

• Fragment-based ligand discovery for proteases, phosphatases, and protein-protein interactions
• Chemical probe development for structural and functional protein studies
• Solid-phase synthesis of peptides, peptidomimetics, and carbohydrates
• Multivalent constructs for enhanced binding and pharmacological properties
• Glycosaminoglycan (GAG) interactions in disease mechanisms
• Synthetic methodology for C-acylation and phosphorus/sulfur ylides

Scientific Awards:

• Innovation Award in Medicinal Chemistry (GDCh/DPhG) (2002)
• Thieme Journal Award (2002)
• DFG Junior Research Group (2002)
• Landesgraduiertenförderung Baden-Württemberg (1994-97)
• Rutgers exchange fellowship (1990)
• Jugend forscht award (1986)

Email: joerg.rademann@fu-berlin.de