معرفی
Professor Judy Hirst is a leading figure at the University of Cambridge, serving as Director of the Medical Research Council Mitochondrial Biology Unit (MRC-MBU) and holding the Professor of Biological Chemistry title. Her research integrates structural, biochemical, and chemical approaches to decode energy conversion mechanisms in complex redox enzymes, particularly mitochondrial respiratory complex I, with implications for human diseases. She is a Fellow of the Royal Society (2018) and the Academy of Medical Sciences (2019).
- Education: MA and DPhil in Chemistry from the University of Oxford
- Postdoctoral: Wellcome Trust Prize International Fellowship at The Scripps Research Institute
Her work focuses on complex I's catalytic mechanisms, reactive oxygen species (ROS) production, and mitochondrial dysfunction in diseases. She pioneers electron cryomicroscopy (cryo-EM) to determine structures of energy-transducing enzymes. Her articles highlight trends in mitochondrial biogenesis, drug inhibition, and redox-driven pathologies.
Scientific Awards:
- Fellow of the Royal Society (FRS, 2018)
- Fellow of the Academy of Medical Sciences (FMedSci, 2019)
- Wellcome Trust Prize International Fellowship
She advises on Natural Sciences (Chemistry) as Director of Studies and acts as a Sustainability Adviser at her college. Her lab's integration with clinical institutions like the NHS underscores the translational impact of her research on mitochondrial diseases and therapeutic development.
