Joseph B. Zwischenberger

Joseph B. Zwischenberger, MD, is a Professor of Surgery and Pediatrics at the University of Kentucky College of Medicine, with affiliations to the Saha Cardiovascular Research Center, CVRC - Affiliated Faculty, and the Surgery/Cardiac MD/PhD Program Mentor. His clinical and research focus spans cardiothoracic surgery, ECMO technology, and critical care innovations, particularly in artificial organ development and postoperative pain management.

• Education: MD from University of Kentucky
• Residency: University of Michigan, Ann Arbor
• Fellowships: Cardiac Division (NIH), Cardiothoracic Surgery, and Critical Care (University of Michigan)
• Certifications: American Board of General Surgery (Vascular and Thoracic Surgery)

His research explores ECMO program development, respiratory failure mechanisms, and congenital heart defect support systems, emphasizing multidisciplinary collaboration in medical device innovation and pediatric cardiovascular care. Key trends include postoperative critical care protocols, tracheal replacement technologies, and surgical education reform to enhance resident autonomy.

Notable scientific contributions include leadership in JACC Scientific Expert Panel on ECMO and foundational work on transhiatal esophagectomy for esophageal carcinoma. His 2023 Annals of Thoracic Surgery article addresses ICU governance models, while his 2024 Ann Thorac Surg Short Rep case study highlights device complication analysis.

As an MD/PhD program mentor, he trains future physician-scientists and collaborates with the Saha Cardiovascular Research Center on translational studies. His work has shaped thoracic surgical protocols, including epidural placement guidelines and Fontan procedure optimization.