Jose Luis Cantero Lorente

Jose Luis Cantero Lorente is a University Professor in the Department of Physiology, Anatomy and Cell Biology at Pablo de Olavide University, specializing in neuroscience with a primary focus on Alzheimer's disease and neurodegenerative disorders. His work bridges electrophysiology, neuroimaging, and biomarker discovery to understand cognitive decline in aging.

Education:

• Doctorate from the University of Seville (1999) with thesis: "Electrophysiological characterization of alpha activity in three states of brain activation in human subjects: relaxed wakefulness, drowsiness and REM phase", supervised by Dr. Carlos María Gómez González.

Research Interests:

Dr. Cantero Lorente's research spans Alzheimer's Disease, Neuroscience, and Biomarkers, with emphasis on early detection mechanisms through salivary, blood, and CSF analysis. He investigates sleep-memory interactions, metabolic drivers of neurodegeneration (e.g., insulin resistance), and neuroinflammatory pathways using multimodal approaches including proteomics, lipidomics, and functional MRI. His pioneering work established salivary lactoferrin as a diagnostic tool for Alzheimer's.

Publication Trends:

His 2022-2025 publications reveal a strategic shift toward multimodal biomarker integration, combining amyloid-beta, tau, and metabolic markers for early Alzheimer's detection. Key themes include Parkinson's disease proteomics (e.g., candesartan neuroprotection), herpes virus-amyloid links in aging, and intracortical myelin alterations as precursors to cognitive decline. Recent work increasingly incorporates machine learning for database analysis and explores angiotensin-based neuroprotective strategies.

Scientific Awards:

No awards were specified in the source material.

Advising and Grants:

He supervises doctoral candidates in the Biotechnology, Biomedicine and Health Sciences program at Pablo de Olavide University, specifically guiding the "Early Detection of Alzheimer's Disease" track. His research is supported by Spain's PAIDI framework (Health Science and Techniques), with projects focusing on interdisciplinary audiological databases and neural network alterations in mild cognitive impairment.

Labs and Teams:

As leader of the LNF Functional Neuroscience research group, he directs studies on electrophysiological correlates of cognitive decline, utilizing EEG, MRI, and molecular techniques to map structural-functional brain changes in Alzheimer's progression. The group collaborates extensively on national initiatives for biomarker validation in neurodegenerative diseases.