معرفی
Joris de Wit is a Professor at KU Leuven's Department of Neuroscience and heads the Laboratory for Synapse Biology at the VIB-KU Leuven Center for Brain & Disease Research. His work focuses on molecular mechanisms of synaptic connectivity, with translational applications in Alzheimer's disease and autism. Supported by ERC and FWO grants, he leads an international team of researchers and trains students through Erasmus programs.
- Education: PhD from VU University Amsterdam (2004), postdoctoral training at VU University (2004-2006) and UCSD (2006-2010)
Research spans cell-surface interactions, synaptic proteomics, and neurodegenerative mechanisms. Key methodologies include transsynaptic mapping, CRISPR-based screens, and advanced electrophysiology units. His 2025 Developmental Cell study reveals GPR158-PLCXD2's role in spine maturation, while 2023 Cell work identifies LRRC37B in human cortical excitability.
- Scientific Awards: ERC Starting Grant, FWO Odysseus Grant
Mentored over 20 PhD and Master's students, including multiple award winners. Institutional roles include Deputy Scientific Director (2018-present) overseeing technology units in FACS, neuroengineering, and proteomics. Organized international workshops like the Lowlands Synapse Symposium.
