Jorge A. Trejo-Lopez

Jorge A. Trejo-Lopez, M.D. is an Assistant Professor in the Department of Laboratory Medicine and Pathology at Mayo Clinic in Rochester, Minnesota, specializing in Neuropathology. His clinical work focuses on Anatomic Pathology with expertise in brain tumor diagnostics and neurodegenerative disease pathology.

Dr. Trejo-Lopez completed his medical training at the University of Florida College of Medicine (M.D. 2014), followed by Anatomic and Clinical Pathology Residency (2018) and Neuropathology Fellowship (2020). He served as Chief Resident during his residency program and maintains active certification in both Anatomic & Clinical Pathology and Neuropathology through the American Board of Pathology.

• 2020: Neuropathology Fellowship, University of Florida College of Medicine
• 2018: Anatomic and Clinical Pathology Residency, University of Florida College of Medicine
• 2014: M.D., University of Florida College of Medicine
• 2010: B.A. in Philosophy and Pre-Professional Studies, University of Notre Dame

His research spans neurodegenerative diseases (particularly Alzheimer's pathology), brain tumor genomics, and diagnostic neuropathology. Recent publications demonstrate expertise in glioma molecular diagnostics, amyloid plaque characterization, and neuroinfectious disease mechanisms. The 15 most recent articles reveal strong emphasis on molecular neuropathology, with recurring themes in TERT mutations, EGFR variants in glioblastoma, and proteomic analysis of neurodegenerative disorders.

Dr. Trejo-Lopez has received multiple teaching and humanism awards including the University of Florida Gold Humanism Honor Society Fellowship and Outstanding Resident Instructor Award. His professional activities include serving as Chair of the Clinical Competency Committee in the Department of Laboratory Medicine & Pathology and active participation in the American Association of Neuropathologists.

• Fellow Teaching Award (2019-2020)
• AANP Neurodegenerative Disease Scholar
• Gold Humanism Honor Society Fellowship
• Outstanding Resident Instructor Award
• Best Quality Improvement Project Award (2019)

His clinical and research work integrates advanced molecular diagnostics with traditional neuropathology, contributing significantly to the understanding of CNS tumor classification and neurodegenerative disease mechanisms. Current projects involve biomarker development for multiple system atrophy and molecular characterization of rare CNS tumors.