معرفی
Dr. Jonathan W. Mueller is Associate Professor of Endocrine Biochemistry at the University of Birmingham, within the School of Medical Sciences and Department of Metabolism and Systems Science. He leads research on protein structure-function relationships, particularly in sulfation pathways regulating steroid hormones, and serves as Department Lead for Equality, Diversity & Inclusion.
Education:
- Habilitation (DSc equivalent), Biochemistry and Molecular Biology, University of Duisburg and Essen, 2012
- PhD in Biochemistry, University of Halle and Wittenberg, 2004
- Biochemistry Diploma (MA equivalent, With Honours), University of Halle and Wittenberg, 2001
His research focuses on enzyme-catalyzed sulfation and desulfation of steroid hormones, with emphasis on PAPS synthases and sulfotransferases. He integrates biochemical, bioanalytical, and cell biological methods with bioinformatics to study protein stability, enzyme interactions, and metabolic regulation. His work spans human and plant systems, promoting interdisciplinary 'red-green' bioscience. He has contributed to understanding genetic defects in sulfation enzymes and their clinical implications.
His recent publications reflect a strong trend in molecular endocrinology, protein biophysics, and cross-kingdom sulfur metabolism. Themes include enzyme stability, protein-protein interactions, redox regulation, and translational insights into steroid disorders. His research is supported by the European Commission, Wellcome Trust, MRC, and Society for Endocrinology.
Scientific Awards:
- Outstanding Teaching Award (2019, 2020)
- Senior Fellow of the Higher Education Academy (2021)
- Fellow of the Higher Education Academy (2019)
- Distinguished Visiting Fellow, Krupp Institute (2015)
Dr. Mueller mentors students and colleagues in teaching excellence and SFHEA applications. He serves as MPharm Tutor for reasonable adjustment plans and is active in the university’s LGBT mentoring programme. His lab welcomes PhD, postdoc, and lab placement applicants. He has secured grants including Marie Curie fellowships, Wellcome ISSF, MRC Proximity-to-Discovery, and Society for Endocrinology funding.
He co-leads the Health Sciences 1 module in the MPharm programme and delivers endocrinology and pharmacology teaching in medicine. He organizes major conferences such as S-Bio and SUPA series. His outreach includes A-level masterclasses and public engagement in EDI, gender, and career development.
