Jonathan Stine

Jonathan Stine is an Associate Professor of Medicine and Public Health Sciences at Penn State College of Medicine, serving as Director of the Fatty Liver Program and Liver Center Research Director. An internationally recognized liver disease expert, his clinical and research focus centers on metabolic dysfunction-associated steatotic liver disease (MASLD) and liver transplantation.

Dr. Stine develops exercise-based interventions as foundational therapies for metabolic liver conditions, establishing multinational clinical guidelines through the American College of Sports Medicine. His NIH-funded research examines mechanisms of exercise benefit in nonalcoholic steatohepatitis and multidisciplinary care models. Recent work demonstrates how advanced liver fibrosis impairs cardiorespiratory fitness and validates the MASH resolution index for clinical trials.

Honors include selection to Stanford's Top 2% Scientists globally, AASLD awards, and recognition from the American Cancer Society. He leads over 30 clinical trials and directs initiatives addressing health disparities in liver disease management.