Jonathan S. Berg

Jonathan S. Berg, MD, PhD, is the Bryson Distinguished Professor in the Departments of Genetics and Medicine at the University of North Carolina School of Medicine. He specializes in clinical and translational genetics, with a focus on cancer genetics and genomic medicine. His roles include Director of the Adult and Cancer Genetics Clinic and the Program in Precision Medicine in Healthcare. Dr. Berg completed his PhD (2001) and MD (2003) at UNC, followed by residency at Baylor College of Medicine (2007) and a postdoctoral fellowship (2009). He is a Fellow of the American College of Medical Genetics and Genomics and co-PI on major grants like ClinGen and NCGENES2. His research integrates next-generation sequencing for gene discovery, diagnostic testing, and population health initiatives, including the Age-Based Genomic Screening project addressing health disparities. Affiliations include the Lineberger Comprehensive Cancer Center and Carolina Institute for Developmental Disabilities.

Research interests span clinical translation of genetic technologies, cancer predisposition genetics, and the cost-benefit analysis of predictive testing. Key contributions include advancing newborn genomic screening and understanding structural variants in cancer. His lab collaborates broadly, with recent publications emphasizing genomic medicine applications and public health implications.