John Yue

John Yue, MD, is an Assistant Professor of Neurological Surgery at UCSF Weill Institute for Neurosciences within the School of Medicine. His clinical and research focus centers on neurotrauma, neurocritical care, intracranial physiology, injury biomarkers, prognostic tools, and traumatic brain injury (TBI) classification systems. He is actively involved in national TBI research initiatives, including the NIH-NINDS TBI Classification Working Group.

Education:

• Residency in Neurological Surgery, UCSF (2025)
• MD, UCSF (2018)
• BA in Molecular and Cell Biology, UC Berkeley (2009)

Dr. Yue's research integrates neuroimaging, molecular biomarkers, and big data analytics to improve TBI diagnosis and outcomes. His work leverages machine learning for injury stratification and has established blood-based biomarkers (GFAP/UCH-L1) as critical diagnostic tools. Current projects include NIH-funded studies on proteomic biomarkers and multicenter cohort analyses through TRACK-TBI.

His publications demonstrate a strong focus on:

• Biomarker validation for TBI diagnosis and outcome prediction
• Healthcare disparities in trauma care
• Long-term neurological and psychiatric sequelae of TBI
• Surgical outcomes and clinical decision-making in neurotrauma

Awards & Grants:

• UCSF Weill Neurohub Clinician-Scientist Award (2025-2026)
• NREF & Bagan Family Foundation Research Award (2022-2023)
• Multiple AANS/CNS awards for neurotrauma research (2021-2024)
• Anthony Marmarou Award for TBI clinical management (2024)

Dr. Yue leads research teams focused on TBI biomarker discovery and big data harmonization. He serves on editorial boards for multiple neurosurgery journals and is an expert panelist for national TBI management guidelines.