John-Paul Yu

John-Paul Yu is an Assistant Professor in the Department of Biomedical Engineering at the University of Wisconsin-Madison, with additional affiliations at the School of Medicine and Public Health. His research focuses on uncovering molecular features of neuropsychiatric diseases through interdisciplinary systems neuroscience and advanced neuroimaging techniques.

His laboratory develops genetic rat models with biallelic knockouts of high-risk genes associated with autism spectrum disorder (ASD) and schizophrenia (SCZ). These models enable systematic interrogation of neuropathogenesis and neuroimaging biomarkers linked to psychiatric illnesses.

Research Interests:

• Genetic animal models of psychiatric disease
• Multimodal neuroimaging and molecular profiling
• Development of gene-specific imaging biomarkers
• Neurodevelopmental disorders