John J. Zone

John J. Zone, MD is a Professor in the Department of Dermatology at the University of Utah, with adjunct appointments in Pathology. Specializing in autoimmune blistering diseases, he maintains dual research and clinical laboratories focused on diagnosis, treatment, and immunopathogenesis of conditions including dermatitis herpetiformis, pemphigus, and linear IgA disease.

• Board Certified: Dermatology, Immunodermatology, Internal Medicine
• Key Research Areas: Autoimmune Skin Disorders, Gluten-related Dermatosis, Transglutaminase Antibodies

His work bridges clinical dermatology and immunological research, with significant contributions to understanding the molecular mechanisms of IgA-mediated skin diseases. Dr. Zone has published extensively on topics including:

• Autoimmune bullous disease pathogenesis
• Celiac disease-dermatitis herpetiformis connections
• Neutrophil adherence mechanisms in IgA dermatoses
• Therapeutic approaches for refractory cases

Scientific contributions include:

• Identifying the 97 kDa linear IgA bullous disease antigen
• Characterizing IgA antibody responses in cutaneous immune disorders
• Developing mouse models for autoimmune skin disease research