John C. Cheville

John C. Cheville, M.D., is a Professor of Laboratory Medicine and Pathology at Mayo Clinic College of Medicine, specializing in urologic malignancies. His research focuses on pathological and molecular features predictive of outcomes in prostate, renal, urothelial, and testicular cancers, alongside applications of rapid imaging technologies in surgical pathology.

• Education:
  • BS, Iowa State University
  • MD, Carver College of Medicine, University of Iowa
  • Internship, Michigan State University
  • Residency, University of Iowa Hospitals and Clinics
  • Residency/Fellowship, Mayo Clinic College of Medicine

His work involves multidisciplinary collaboration, integrating large clinical registries and genomic sequencing to identify therapeutic targets, and developing 3D microcancer models for drug testing. He pioneered infrared-optical hybrid microscopy for real-time intraoperative tissue analysis.

Dr. Cheville has received awards including the Mayo Clinic Distinguished Clinician Award (2019) and the William B. Zeiller Professorship (2022). He has held leadership roles such as Chair of the Division of Anatomic Pathology (2005-2008) and Co-director of the Biomarker Discovery Program (2008-2019).