Joe El-Khoury

Joe El-Khoury is a Professor of Laboratory Medicine and Director of the Clinical Chemistry Laboratory at Yale School of Medicine. He holds dual roles as Director of Clinical Chemistry and the Clinical Chemistry Fellowship Program at Yale New Haven Health. His research focuses on improving kidney function biomarkers, clinical laboratory performance, and mass spectrometry applications. He completed his PhD at Cleveland State University and postdoctoral training at Cleveland Clinic.

Education: PhD (Cleveland State University, 2012), BS (American University of Beirut, 2008), Postdoctoral Fellowship (Cleveland Clinic, 2014). Advanced certifications include Yale School of Management programs (2017-2018).

Research interests include SDMA as a kidney function biomarker, mass spectrometry adoption in clinical labs, and reducing pre-analytical errors. He has developed novel assays and contributed to lipid testing guidelines through ADLM collaborations.

Recent articles focus on hepatitis C serology assays, creatinine delta thresholds for AKI, and trimester-specific haptoglobin reference intervals. His work emphasizes diagnostic accuracy and laboratory automation advancements.

Notable awards include 2024 SYCL Mentor of the Year and 2023 IFCC Young Investigator Award. He serves as a reviewer for Clinical Chemistry, The Journal of Applied Laboratory Medicine, and others.

His team addresses fluid contamination detection using machine learning and evaluates new clinical assays for diagnostic reliability. Current projects include high-throughput SDMA assays and improving creatinine-based eGFR equations.