معرفی
Dr. Jim Xiang is a Professor in the Division of Experimental Oncology, Department of Oncology at the University of Saskatchewan, and an Associate Member in the Department of Pathology. His research focuses on understanding cellular and molecular mechanisms governing CD4 T cell assistance in CD8 T cell responses, memory formation, and developing exosome-targeted immunotherapies for HER2-positive breast cancer and HIV. Recent work revealed the critical role of M6PR in regulating T cell fate, with ongoing studies investigating cytokine-induced M6PR pathways in T cell survival and memory. His lab explores novel vaccine strategies and immunometabolic pathways (e.g., AMPK, mTORC1) in T cell function.
Key research interests include:
- Mechanisms of T cell immunity and memory
- Exosome-based cancer immunotherapy
- Immunometabolic pathways in T cell regulation
- Immunomodulation of tumor microenvironments
Dr. Xiang’s publications span topics like T cell memory dynamics, cytokine signaling, and vaccine design, with emphasis on translational applications in oncology and infectious diseases. His work integrates molecular biology, immunology, and systems biology approaches to address clinical challenges in cancer and viral immunity.
