Jie Zhang

Jie Zhang is an Associate Professor in the Department of Pharmacology & Immunology at the Medical University of South Carolina (MUSC), affiliated with the College of Medicine. His research focuses on redox biology, cancer biology, immunology, and drug development, with an emphasis on mechanisms of oxidative stress, protein modifications, and therapeutic targeting of redox pathways. He holds a PhD in Pharmaceutical Sciences from Katholieke Universiteit Leuven (Belgium, 2008), a Master's from the same institution (2004), and a Bachelor's in Pharmacy from Zhejiang University (China, 2001).

His research interests include the role of redox signaling in cancer progression, mitochondrial dysfunction, and drug resistance. He investigates molecular mechanisms of protein S-glutathionylation, thioredoxin reductase inhibition, and glutathione transferase regulation in disease contexts such as Parkinson’s, melanoma, and lung cancer. His work also explores novel drug candidates targeting redox pathways, including Michael addition drugs and cannabinoids.

Publications highlight his contributions to understanding redox-mediated apoptosis, ER stress responses to mechanical stimuli, and the interplay between oxidative stress and viral infections. His studies often bridge basic biochemical mechanisms with translational drug development strategies.

While no formal awards are listed, his extensive publication record reflects sustained contributions to pharmacology and redox biology. His research has implications for novel therapeutic approaches in oncology, neurodegenerative diseases, and smoking-related pathologies.