معرفی
Jhih-Rong Lin is a Research Assistant Professor in the Department of Genetics at Albert Einstein College of Medicine. His research focuses on understanding the genetic and genomic mechanisms underlying complex human diseases, particularly neurodegenerative disorders, longevity, and developmental syndromes. He employs computational and systems biology approaches to analyze genomic data, identify disease risk genes, and model genetic pathways.
Key research themes include:
- Genetic variants associated with aging and neurodegeneration (e.g., Alzheimer’s disease, schizophrenia)
- Post-GWAS analysis for disease gene prioritization (e.g., using tools like PGA)
- Evolutionary genomics of longevity (e.g., studies on beaver genomes)
- Epigenetic regulation in cancer progression and development
Lin’s work bridges computational methods with experimental validation, contributing to drug discovery for aging-related conditions and improving understanding of genetic modifiers in syndromic disorders. His recent publications highlight discoveries in rare variant analysis, polygenic risk prediction, and systems-level aging mechanisms.
