Jeroen Demmers

Jeroen Demmers is an Associate Professor at Erasmus MC in the Department of Biochemistry, with expertise in proteomics, transcription, mass spectrometry, and ubiquitin signaling pathways. His research focuses on DNA repair mechanisms (nucleotide excision repair, base excision repair), stem cell biology, and neural differentiation, while also contributing to vaccine design through HLA immunopeptidome analysis.

• Key research areas:
  • Proteomics and mass spectrometry for molecular profiling
  • Ubiquitin-mediated protease activity in gene regulation
  • DNA damage response in cellular dynamics
  • Epigenetic control of stem cell and neuronal differentiation
  • HLA-based vaccine development for immunotherapy

His recent publications address topics such as K63-linkage deubiquitinase activity, CHD8-TRRAP gene regulation, and mosquito saliva effects on West Nile virus pathogenesis. These studies span disciplines including biochemistry, molecular biology, and immunology, with applications in neurological disorders, cancer biology, and virology.