معرفی
Jeremy Bird is an Assistant Professor in the Department of Biological Sciences at the University of Delaware’s College of Arts & Sciences. His research focuses on the interplay between cellular metabolism and transcriptional regulation, particularly the role of non-canonical initiating nucleotides (NCINs) in RNA capping. He holds a BS from Loyola University in Maryland, a PhD from Cornell University, and completed post-doctoral research at Rutgers University’s Waksman Institute of Microbiology.
Dr. Bird’s work investigates how metabolic states influence transcription by RNA polymerases, with emphasis on mitochondrial RNAPs and their use of NAD(H) and dpCoA as capping metabolites. His lab employs genetic, biochemical, and next-generation sequencing approaches to study transcription initiation, elongation, and termination dynamics. Key discoveries include NAD-cap-dependent regulation of RNA stability and its redox-state sensitivity, suggesting a novel epitranscriptomic regulatory layer.
Recent projects explore functional implications of metabolite caps, metabolic/transcriptional crosstalk, and applications to mitochondrial dysfunction in diseases. His research has been published in high-impact journals, with a focus on mechanistic studies of transcriptional regulation across prokaryotes and eukaryotes.
