معرفی
Jeongjoon Choi is a Research Scientist in the Department of Genetics at Yale University, affiliated with the Yale School of Medicine. He holds a PhD from Seoul National University (2010) and is part of the DiMaio Lab. His research focuses on understanding virus entry mechanisms in human papillomavirus (HPV) and bacterial virulence pathways in Salmonella. Key areas include HPV trafficking through cellular compartments, interactions between viral capsid proteins and host machinery, and regulatory mechanisms governing Salmonella pathogenesis.
Dr. Choi’s work on HPV explores how viral particles utilize cellular proteins like Rab6a and BICD2/dynein to navigate endosomal networks during infection. For Salmonella, he investigates how environmental signals (e.g., pH, host factors) trigger virulence programs and modulate gene expression of horizontally acquired genes. His studies highlight the interplay between bacterial adaptation and host immune evasion strategies.
Recent publications emphasize breakthroughs in understanding disordered protein regions in HPV L2 capsid proteins and non-canonical Rab9a roles in endosomal exit pathways. Collaborations with colleagues such as Daniel DiMaio and Eduardo Groisman underscore interdisciplinary approaches to pathogen biology. No specific awards are listed, but his lab’s findings have been featured in high-impact journals like *PLOS Pathogens* and *MBio*.
Dr. Choi’s research also extends to translational applications, such as dual-therapeutic strategies for septic arthritis, demonstrating a balance between fundamental and applied microbiology. His work contributes to both academic and clinical advancements in infectious disease research.
