معرفی
Jeffrey Yap is a Research Professor in the Department of Radiology and Imaging Sciences at the University of Utah. He serves as the Director of the Center for Quantitative Cancer Imaging and Theranostics (CQCIT), a multidisciplinary hub integrating radiopharmaceutical development, preclinical and clinical imaging, and theranostic technologies. His research focuses on quantitative multimodality imaging to evaluate novel cancer therapies in murine tumor models and clinical trials, with expertise in PET/CT, SPECT/CT, and theranostic radiopharmaceuticals. He holds a PhD in Medical Physics from the University of Chicago and a BS in Physics from the University of Dallas.
- Education
- PhD in Medical Physics, University of Chicago
- BS in Physics, University of Dallas
- Research Interests
- Quantitative imaging for cancer therapy evaluation
- Theranostics (diagnostic and therapeutic radiopharmaceuticals)
- 4D PET/CT in radiation treatment planning
- Body composition analysis in oncology
- Preclinical and clinical trial imaging
- Hypoxia and metabolic PET biomarkers
- Scientific Contributions
- Developed standardized imaging protocols for clinical trials (e.g., UPICT)
- Characterized autophagy resistance mechanisms in RAS-driven cancers
- Validated FDG-PET as a pharmacodynamic biomarker for targeted therapies
- Integrated body composition metrics into cancer survival analysis
- Laboratory & Facilities
- Director of CQCIT, operating two cGMP cyclotron labs
- North American Mediso Preclinical Imaging Center of Excellence
- Advanced digital PET/CT/SPECT/CT for clinical trials
- Image Analysis Core with Yunu software for tumor measurement
۰مقاله منتشرشده
