Jeffrey Tseng

Jeffrey Tseng is an Associate Professor at Wayne State University with joint appointments in the Department of Molecular Medicine and Genetics and the Department of Biochemistry, Microbiology, and Immunology. His research integrates structural biology, molecular evolution, and computational approaches to study protein and RNA structures.

• Office: 3220 Scott Hall, Detroit, MI 48201
• Contact: 313-577-0498 | ytseng@wayne.edu

Research Focus

Dr. Tseng's work centers on geometric analysis of biomolecular structures, with applications in:

• Protein shape analysis for functional classification
• Disease-associated mutation modeling (e.g., nsSNPs)
• Knot theory in RNA structure prediction
• High-throughput surface patch generation for drug discovery
• Evolutionary matching techniques
• Structural variations in gene duplication

Publication Trends

His recent publications highlight cross-disciplinary approaches combining:

• Structural biology of regulatory proteins (ABHD5)
• Computational modeling of viral-host interactions
• Evolutionary constraints in RNA viruses
• Machine learning applications for mutation impact prediction
• High-performance computing in structural analysis
• Translational applications for metabolic and infectious diseases

Academic Engagement

Dr. Tseng is actively mentoring PhD and Master's students, with laboratory facilities for structural modeling and computational biology research.