Jeffrey A. Wong

Jeffrey A. Wong, MD is an Associate Professor in the Department of Medicine at the University of California, Irvine School of Medicine. His research focuses on endocrinology and women's health, particularly on the bioactivity of phytoestrogens in herbal remedies.

• University: University of California, Irvine
• School: School of Medicine
• Department: Department of Medicine
• Academic Rank: Associate Professor

Dr. Wong specializes in hormone replacement therapy and phytoestrogen research, investigating the estrogenic effects of plants like soy, red clover, licorice, and hops. His work has shown high estrogen activity in fo-ti (Polygonum multiflorum), while disproving activity in chaste tree berry, black cohosh, and dong quai. He developed a recombinant cell bioassay for estradiol and studies how glycone group removal affects soy's estrogenic potency.

Scientific studies using his methods have been cited in various publications, including research on:

• Phytoestrogens and bone health
• Liquiritigenin receptor selectivity
• Black cohosh opioid activity
• Red clover reproductive effects
• Licorice toxicity concerns

His work aims to provide standardized methods for measuring plant-based estrogen activity and inform clinical studies on dietary supplements for menopausal women.