Jeff B Boissoneault

Jeff B Boissoneault is an Associate Professor in the Department of Anesthesiology at the University of Florida, College of Medicine. He holds a PhD and is actively involved in research focusing on the intersection of chronic pain, alcohol use, and neurobiobehavioral mechanisms. His work spans clinical, experimental, and longitudinal studies, particularly in populations such as older adults and individuals with temporomandibular disorders (TMD) and chronic low back pain.

His research interests center on understanding how pain and alcohol interact, including alcohol's analgesic effects, changes in brain functional connectivity following alcohol consumption, and the impact of chronic pain on decision-making and substance use. He employs neuroimaging techniques, behavioral assessments, and ecological momentary assessment to capture real-world dynamics.

The recent publications highlight a strong trend in investigating dose-dependent alcohol effects on pain thresholds, neural correlates of chronic pain (e.g., brain entropy), and social functioning in adolescents with pain. His work frequently explores functional connectivity, particularly in the insula and prefrontal cortex, under the influence of alcohol.

Dr. Boissoneault is Principal Investigator on multiple NIH-funded projects, including:

• Effects of Pain on Laboratory Drinking Topography and Daily Drinking in People with Chronic TMD Pain
• Determining the Longer-term Impact of Covid-19 Stressors, Alcohol Use and Neurobiobehavioral Decline in Older Adults Through Prospective Study
• Mechanisms and Modification of Pain Modulatory Capacity
• Characterizing the effects of family history of alcoholism on alcohol analgesia

These grants reflect a sustained focus on alcohol-pain interactions, aging, and neurobiological resilience.

He has published 85 research outputs, with a consistent publication record from 2008 through 2025. While specific advisees are not listed, his role as PI and frequent collaboration with junior researchers suggests active mentorship. His work contributes to UN Sustainable Development Goals related to health and well-being.