Jean-Luc Mougeot

Jean-Luc Mougeot, Ph.D., is an Adjunct Professor at Carolinas Medical Center - Cannon Research Center (CMC-Atrium Health), Charlotte, NC. He holds a Ph.D. in Cellular and Molecular Biology from Université Louis Pasteur, Strasbourg, France (1995). His professional roles include Director positions in Molecular Biology, Translational Research, and Therapeutic Development, as well as leading research groups in Oral Medicine and Microbiomics.

Research interests focus on genomic and microbiomic biomarkers for systemic and oral diseases, including Sjögren’s syndrome, infective endocarditis, cancer therapy complications (e.g., oral mucositis, radiation caries), and cardiovascular disease. His lab employs next-generation sequencing, computational biology, and functional assays to identify genetic risk factors and develop diagnostic tools. Key projects include studying collagen SNPs in radiation-induced periodontal damage, biomarkers for rheumatic diseases, and microbiome shifts in hematological cancer patients.

Publications include seminal work on SNP identification in periodontal disease using exome sequencing. His work integrates molecular biology, bioinformatics, and clinical data to advance translational medicine.