معرفی
Jason Newbern is an Associate Professor in the School of Life Sciences at Arizona State University (ASU), with affiliations at the Neurodegenerative Disease Research Center and Neuroscience (PhD) program. His research focuses on cellular and molecular mechanisms of nervous system development, particularly ERK/MAPK signaling in neurodevelopmental disorders like RASopathies and autism spectrum disorders. Dr. Newbern earned his PhD from Wake Forest University School of Medicine (2006) and a BS from the University of Michigan-Ann Arbor (2000). His work combines mouse genetics, pharmacology, and advanced imaging to study neural circuit formation in vivo, with recent studies exploring how aberrant ERK1/2 signaling contributes to developmental deficits.
Research highlights include defining ERK pathway functions in cortical and spinal circuits, collaborations on addiction and neurodegeneration, and investigations into therapeutic interventions for neurodevelopmental disorders. He teaches courses in developmental biology, neurobiology, and molecular biology, mentoring students in PhD and undergraduate programs. Newbern leads an NIH-funded project examining GABAergic circuit defects caused by ERK hyperactivity and participates in multi-institutional grants on brain injury and endorphin pathways.
His lab’s expertise spans neuroimaging, viral tracing, and transcriptomics, with ongoing work on the relationship between developmental signaling and complex behaviors. Collaborations with researchers across disciplines ensure translational insights into mechanisms underlying autism, RASopathies, and neurodegenerative diseases.
