Jason Cain

Dr. Jason Cain is an Adjunct Associate Professor (Research) at Hudson Institute of Medical Research's Centre for Cancer Research, leading the Developmental and Cancer Biology research group and the Sarcoma Program. He specializes in developmental biology and pediatric cancers, focusing on embryonic signaling pathways (e.g., Hedgehog) and epigenetic mechanisms in diseases like sarcomas, pediatric brain tumors (diffuse intrinsic pontine glioma), and lung cancer. He completed his PhD in Anatomy and Cell Biology at Monash University (2006) and postdoctoral training at The Hospital for Sick Children in Toronto, Canada.

Education:

• BSc (Monash University, 2000)
• BSc(Hons) (Monash University, 2001)
• PhD in Anatomy and Developmental Biology (Monash University, 2006)

Research Interests:

• Role of Hedgehog and BMP signaling in kidney development and cancer
• Epigenetic regulation in pediatric cancers
• Therapeutic targeting of metabolic pathways in diffuse midline gliomas
• Development of precision vaccines for pediatric brain tumors

Key Projects:

• Advancing differentiation therapy for pediatric high-grade gliomas (2025–2028)
• Victorian Paediatric Cancer Consortium (2021–2025)
• Precision vaccines for pediatric brain tumors (2021–2025)
• My Room Children's Cancer Charity Fellowship (2024–2028)

Grants & Labs:

• Laboratory: Developmental and Cancer Biology Lab
• Focus: Sarcoma Program leadership and collaborative research networks across Australia and globally