Janine Lupo

Janine Lupo, PhD, is a Professor in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco (UCSF). She holds affiliations with the Surbeck Laboratory of Advanced Imaging and Neuroimaging Research Interest Group, as well as the UCSF/UC Berkeley Graduate Group in Bioengineering, Helen Diller Family Comprehensive Cancer Center, Institute for Computational Health Sciences, and Quantitative Biosciences Institute. Her research focuses on developing novel MRI techniques for neurological disease evaluation, with applications in brain tumor imaging and therapy monitoring.

Dr. Lupo completed her BSE in Bioengineering at the University of Pennsylvania (1997–2001) and her PhD in Bioengineering at UCSF/UC Berkeley (2001–2006). She conducted postdoctoral training in High Field MRI of Brain at UCSF (2006–2010) before joining the faculty. She has served as Principal or Co-Principal Investigator on over a dozen NIH and DoD grants, including leadership roles in NIH Programmatic Project Grants and Brain Tumor SPORE initiatives.

Her research interests span ultra-high field MRI, algorithm development, imaging biomarkers, and statistical modeling for brain tumors and neurological conditions. Notable projects include AI-driven response assessment in neuro-oncology (AI-RANO), MRI-based therapy monitoring, and 7T MRI advancements for Huntington’s disease and glioma evaluation.

Award highlights include the Johnson & Johnson Women in STEM2D award (2017), NIH Clinical Loan Repayment Program awards (2010, 2012), and multiple UCSF RAP grants. She has authored over 75 peer-reviewed articles and contributed to clinical guidelines through collaborations with the Response Assessment in Neuro-Oncology (RANO) group.

Her work bridges clinical and translational research, with grants spanning 2005–2024. Current efforts emphasize preanalytic factors in brain tumor studies, imaging biomarker validation, and ethical considerations in precision medicine imaging.