معرفی
Jane Carr-Wilkinson is a Senior Lecturer in Pathology at the University of Sunderland's School of Medicine, specializing in neuroblastoma research and stem cell modeling. She leads phase one MBChB Medicine curriculum components in physiology and pathophysiology while contributing to international collaborative teaching initiatives as PVC Learning and Teaching Fellow in Transnational Education.
Her research program investigates neuroblastoma pathogenesis through human pluripotent stem cell differentiation to neural crest cells, focusing on the molecular interplay between development and cancer initiation. She explores stemness genes, LGR5/WNT signaling pathways, and clonal evolution mechanisms in drug resistance.
Article analysis reveals 15 years of publication activity (2003-2022) centered on neuroblastoma genetics (p53 pathway, MYCN), stem cell modeling, and drug resistance mechanisms. Collaborations with Newcastle University feature prominently, particularly in neurotoxicity studies of IPSC-derived neurons.
Scientific awards include Senior Fellow of the Higher Education Academy. She co-investigates neurotoxicity mechanisms with Newcastle University and engages in Cancer Research UK's Race for Life initiatives.
