Jan van Laar

Dr. Jan van Laar is a researcher at Erasmus MC, affiliated with the Department of Immunology and the Department of Internal Medicine. His work bridges clinical medicine and immunological research, focusing on complex inflammatory and autoimmune conditions.

His research interests center on immunology and rheumatology, particularly IgG4-related disease, Behçet’s disease, sarcoidosis, uveitis, and histiocytic disorders. His work integrates clinical observation with molecular analysis to improve diagnosis and treatment.

The recent publications highlight a strong trend in investigating rare immune-mediated diseases, with a focus on identifying diagnostic biomarkers (e.g., red flags for IgG4-RD), exploring targeted therapies (e.g., JAK inhibitors), and understanding disease mechanisms through genetic profiling (e.g., MAPK pathway mutations). His research spans clinical trials, case reports, and systematic reviews, demonstrating a comprehensive approach to advancing patient care.

• Active contributor to high-impact journals including The Lancet Rheumatology, Blood Advances, and BMJ Open.
• Involved in multicenter collaborative research, including the DRIMID study.
• Supervised 9 research works, indicating active mentorship of junior researchers.
• Contributor to datasets on rare autoinflammatory syndromes, suggesting involvement in translational research and health impact assessment.