P. Martin van Hagen

P. Martin van Hagen is a Full Professor at Erasmus MC, Department of Internal Medicine, with a strong focus on Immunology. His research integrates clinical immunology with translational approaches to understand immune dysregulation in diseases such as uveitis, sarcoidosis, and common variable immunodeficiency. He is actively involved in biomarker discovery and immune profiling, contributing significantly to diagnostic and therapeutic advancements.

His research interests lie at the intersection of autoimmune diseases, ocular inflammation, and primary immunodeficiencies. He has pioneered work on serum biomarkers like BAFF, CXCL9, and C1q for differential diagnosis of uveitis etiologies. His studies on T-cell and B-cell responses, particularly in sarcoidosis and IRF2BP2 deficiency, highlight his expertise in immune pathogenesis. He also contributes to nuclear medicine applications, including somatostatin receptor scintigraphy.

The recent publications demonstrate a consistent focus on immune-mediated ocular diseases, biomarker validation, and genetic immunodeficiencies. His work spans clinical diagnostics, molecular immunology, and therapeutic innovation, often involving multi-center collaborations and advanced immunological assays.

• Supervises research projects and contributes to academic training (23 supervised works documented).
• Active in national and international collaborations, particularly in immunology and ophthalmology networks.
• Engaged in translational research with potential for clinical implementation in autoimmune and infectious eye diseases.

He leads a research program within the Immunology division at Erasmus MC, focusing on immune dysregulation and diagnostic innovation. His team collaborates with ophthalmologists, infectious disease specialists, and molecular biologists to advance understanding and management of complex inflammatory conditions.