معرفی
Jan Skotheim is a Professor of Biology at Stanford University and holds a courtesy appointment in Chemical and Systems Biology. He is a member of Bio-X and the Stanford Cancer Institute. His research focuses on understanding how cell growth determines the timing of cell division, with implications for fundamental cell biology and cancer therapy.
- PhD, Applied Mathematics, University of Cambridge (2004)
- CASM Pt III, Applied Mathematics, University of Cambridge (2001)
- BS, Mathematics, MIT (1999)
- BS, Physics, MIT (1999)
His interdisciplinary research combines mathematical modeling, quantitative imaging, and molecular genetics to study:
- Mechanisms of cell size control through protein dilution
- Conservation of growth-division coupling across eukaryotes
- Cell size-dependent proteome remodeling
- Transcriptional scaling with cell size
- Novel cancer therapy targets like UBR5
His recent publications reveal conserved principles of genome concentration effects on transcription in bacteria and eukaryotes, phosphorylation dynamics controlling cell cycle entry, and diffusion biophysics in fission yeast. These studies span molecular systems biology, cancer biology, and developmental contexts.
Scientific honors include:
- NIH Postdoctoral Fellowship
- Burroughs Wellcome Fund Career Award
- NSF CAREER Award
- HHMI/Gates/Simons Foundation Faculty Scholar
He advises doctoral students and postdoctoral researchers while leading graduate programs in Biology, Biophysics, and Chemical and Systems Biology. His lab collaborates with the Chan Zuckerberg Biohub Cell Atlas Project to integrate cell size data into single-cell sequencing workflows.
