Jan Gründemann

Prof. Dr. Jan Gründemann serves as a Group Leader at the German Center for Neurodegenerative Diseases (DZNE) in Bonn, Germany. His research program investigates fundamental mechanisms of memory formation and neuronal computation using advanced circuit neuroscience methodologies.

His primary research interests include:

• State-dependent sensory integration in memory processes
• Neuronal network dynamics in deep brain regions
• Optogenetic and pharmacogenetic manipulation techniques
• Two-photon imaging of neuronal activity
• AI-driven analysis of neural coding
• Pathophysiological mechanisms in neurodegenerative disorders

Dr. Gründemann's laboratory employs an integrative approach combining cutting-edge experimental techniques with computational modeling to elucidate how neuronal circuits support memory functions in health and disease. His work bridges molecular/cellular neuroscience with systems-level behavioral analysis, focusing on calbindin-positive neuronal populations and their role in information processing.