James Stoll

James Stoll is an Associate Professor in the Department of Pharmaceutical Sciences at Texas Tech University Health Sciences Center School of Pharmacy in Amarillo, Texas, a position he has held continuously since July 1996.

His educational background includes a PhD in Biochemistry from Johns Hopkins University School of Public Health (1980-1987) and a BS in Chemistry from New Mexico State University (1977-1980).

Dr. Stoll's research focuses on neuroscience and biochemistry with specialized expertise in Down syndrome and Alzheimer's disease pathophysiology. He has pioneered work using Ts65Dn mouse models to investigate cognitive impairment mechanisms, mitochondrial dysfunction (particularly cytochrome oxidase deficiencies), and neurotransmitter system alterations. His pharmacological studies span ion channel regulation, blood-brain barrier transporters, and dietary interventions for neurological disorders.

Analysis of his 27 publications reveals consistent investigation of neurodegenerative mechanisms across two decades, with particular emphasis on calcium/sodium channel expression in trisomy models and metabolic therapies for seizure disorders. His work demonstrates rigorous biochemical methodology applied to complex neurological questions.