James O'Donnell

James O'Donnell is an Associate Professor in the Department of Cellular and Molecular Pharmacology at the College of Pharmacy, Rosalind Franklin University. His academic work bridges foundational sciences, pharmacology, and clinical applications with a focus on vascular biology and drug safety.

Dr. O'Donnell's research spans Pharmacology, Molecular Pharmacology, and Vascular Biology, investigating mechanisms of endothelial permeability, drug-induced toxicity, and forensic pharmacology. His work examines VEGF receptor signaling in cyclic stretch responses, connexin43 in lung vascular permeability, and microRNA regulation in inflammatory pathways. He also explores clinical applications through drug toxicity analyses and medicolegal pharmacology.

Analysis of his 15 most recent publications (2004-2020) reveals two distinct research phases: early polymer chemistry work (2004) and a sustained focus on vascular biology (2010-2020). Current research emphasizes mechanotransduction in endothelial cells, forensic pharmacology applications, and molecular pathways in drug-induced liver injury. Key journals include Journal of Biological Chemistry, PLoS One, and Drug Safety publications.

He serves as editor for Drug Discovery and Development (2020) and the 4th edition of O'Donnell's Drug Injury (2016), with numerous book chapters on marijuana pharmacology, endocrine disorders, and drug testing. His work maintains strong clinical relevance through collaborations with medical practitioners and legal professionals.