معرفی
James Neil Hickey is a Researcher at the University of Trieste's Department of Chemical and Pharmaceutical Sciences, specializing in biocrystallography and electrochemical studies of redox proteins. He actively contributes to multiple research groups including the CEB Group, Vitamin B-12 chemotherapeutic agents Group, and Redox proteins Group, focusing on structural biology, drug design, and supramolecular chemistry.
- Research Interests
- Biocrystallography of natural/artificial proteins
- Electrochemical analysis of redox proteins
- Vitamin B12 bioconjugates for targeted therapy
- Host-guest chemistry in supramolecular systems
- Molecular recognition in enzyme catalysis
His research involves characterizing protein crystals (e.g., HIV protease inhibitors, cytochrome c variants) and developing chemotherapeutic agents using vitamin B12 functionalization. Recent projects include Flexible molecular crystals with embedded electrical fields (FLEXPOLE) with Silvano Geremia as PI.
Key collaborations span structural biology, electrochemistry, and nanotechnology. Affiliated with research groups studying metalloproteins, supramolecular polymers, and biocrystallographic applications in drug delivery.
