معرفی
James Macy Jr. is a Professor in the Department of Comparative Medicine at Yale School of Medicine, where he also serves as Vice Chairman for Clinical Affairs, Attending Veterinarian, and Director of the Yale Animal Resources Center. His academic and administrative roles place him at the forefront of laboratory animal care and research support at Yale.
Research Interests:
- Comparative and laboratory animal medicine
- Pathogenesis and transmission of viral diseases in rodent models
- Mouse models of diabetes and obesity
- Co-infections involving Helicobacter and viruses
- Animal facility biosecurity and husbandry practices
His research, particularly through the Mouse Metabolic Phenotyping Center (MMPC), focuses on advancing the in vivo characterization of mouse models for metabolic diseases. The publications reflect a long-standing interest in ensuring the health and integrity of research animal colonies, especially in immunocompromised models.
Scientific Publications Trends: His scholarly output spans from clinical case reports in non-human primates to large consortium-based metabolic phenotyping efforts. The articles demonstrate a consistent focus on viral pathogenesis in laboratory animals, transmission dynamics, and the impact of environmental and immunological factors on disease expression. Recent work emphasizes collaborative, resource-driven science to support translational research in diabetes and obesity.
Advising and Grants: While no formal students are listed, his leadership in core facilities and research consortia suggests mentorship of trainees and researchers utilizing animal models. His involvement in the MMPC indicates participation in NIH-funded grant-supported infrastructure, contributing to national research capabilities in metabolic disease.
Laboratories and Teams: Dr. Macy is closely affiliated with the Yale Animal Resources Center and the Mouse Metabolic Phenotyping Center. He collaborates extensively with researchers such as Caroline Zeiss, Gerald Shulman, and Rachel Perry, contributing expertise in animal health and model validation to interdisciplinary teams.
