معرفی
Dr. James Green is a Professor of Organic and Organometallic Chemistry at the University of Windsor's Faculty of Science. His research focuses on metal-mediated synthetic methods, particularly using cobalt complexes to stabilize reactive intermediates like γ-carbonyl cations and cycloheptyne systems. He has contributed to the synthesis of natural products such as velloziolide and microstegiol, as well as antitumor allocolchicines like NSC 51046. His work bridges fundamental organometallic chemistry with practical applications in drug discovery and organic synthesis.
Education: B.Sc. (1982) University of Windsor; Ph.D. (1987) University of Waterloo (advisor V.A. Snieckus). Postdoctoral training at UC Berkeley (advisor K.P.C. Vollhardt). Honors include NSERC University Research Fellow (1989-1999).
Research Interests:
- Transition metal-catalyzed reactions (e.g., Nicholas Reaction)
- Cobalt-mediated stabilization of reactive intermediates
- Synthesis of complex natural products
- Dehydrotropylium ion complexes and aromaticity studies
- Alkynedicobalt complexes in cyclopropanation and alkynylation
Key Achievements:
- Developed cobalt-based methods for γ-carbonyl cation generation
- Patented catalytic dibenzocycloheptane synthesis (US Patent 9,573,873)
- Guided over 30 graduate and undergraduate researchers
- Recipient of prestigious NSERC fellowship supporting 10 years of research
Labs/Teams: Leads an active research group in the Department of Chemistry, focusing on organometallic synthesis and catalysis. Collaborates with institutions like Accucaps and Emory University on applied chemistry projects.
