معرفی
James D. Lauderdale is an Associate Professor and Department Head of Cellular Biology at the University of Georgia. His research focuses on the molecular genetic mechanisms underlying vertebrate eye and forebrain development, utilizing genetic approaches in humans, mice, zebrafish, and other model organisms.
- Investigates PAX6 gene mutations causing aniridia and Small eye traits.
- Identified the novel LFDC gene linked to eye development.
- Collaborates with Drs. Nadean Brown and Grant Mastick to identify Pax6-regulated genes.
- Uses zebrafish for live imaging and experimental manipulation of neural development.
His work contributes to understanding CNS development and potential therapeutic interventions. Recent publications emphasize FRET imaging, ratiometric signal analysis, and evolutionary conservation of Pax6 isoform regulation.
Lauderdale's lab employs advanced techniques in chromatin assembly, gene expression, and axon tract studies, with a long-term goal of correcting genetic and acquired CNS damage through developmental insights.
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