معرفی
James B. Gloer is the Roy J. Carver/Ralph L. Shriner Professor of Chemistry at the University of Iowa’s Department of Chemistry. His research focuses on the discovery, isolation, and structure determination of biologically active natural products from fungi, with applications in anticancer, antifungal, and agricultural sectors. He holds a PhD from the University of Illinois and a BS from the University of Florida.
- Education: PhD (University of Illinois), BS (University of Florida)
His research program emphasizes fungal chemical ecology, targeting underexplored fungi for novel metabolites. Using bioassays (antifungal, antibacterial, antiinsectan, anticancer) and advanced chromatographic/NMR techniques, his team investigates interspecies competition metabolites and fungi that attack other organisms as sources of antifungal agents. Key areas include coprophilous fungi and their defensive mutualism roles.
Recent publications (2020–2016) highlight fungal metabolites with anticancer activity (e.g., Campafungins), environmental photochemical transformations (e.g., trenbolone derivatives), and plant-fungal interactions in peanut seeds. Articles span organic chemistry, environmental science, and marine/microbial natural products.
- Scientific Awards: Alfred P. Sloan Foundation Fellow (1990–92), NIH Research Career Development Award (1990–95), 2007 Regents Award for Faculty Excellence, 2010 Graduate College Outstanding Faculty Mentor Award, Norman R. Farnsworth Research Achievement Award (2018).
Collaborations with mycologists and interdisciplinary teams drive his work. Techniques include HPLC, high-resolution mass spectrometry, and 2D-NMR for structural analysis. The Gloer Research Group website details projects on fungal secondary metabolites and their therapeutic potential.
