Jakob Theorell

Jakob Theorell is a Research Fellow at the University of Oxford's Nuffield Department of Clinical Neurosciences, working within the Autoimmune Neurology Group under Professor Sarosh Irani. His research focuses on cellular immunological mechanisms in Autoimmune Encephalitides and clinical management of complex cases at the neurology-psychiatry-immunology interface.

Education

• PhD from Karolinska Institutet (supervised by Professor Yenan Bryceson at the Center for Hematology and Regenerative Medicine, Department of Medicine, Huddinge)
• Thesis: "Chronic Human Immunodeficiency Syndromes Affecting Lymphocyte Cytotoxicity"

Research Focus

Dr. Theorell specializes in the cellular immunology of Autoimmune Encephalitides, investigating how immune dysfunction targets neural tissues. His work bridges neurology, psychiatry, and immunology to address diagnostic and therapeutic challenges in patients with overlapping neurological and psychiatric symptoms. This interdisciplinary approach aims to develop targeted immunotherapies for autoimmune neurological disorders.

Research Group Affiliation

As a core member of Oxford's Autoimmune Neurology Group, he contributes to translational research projects examining T-cell and antibody-mediated mechanisms in autoimmune CNS disorders, collaborating closely with clinical and laboratory teams to advance diagnostic biomarkers and treatment protocols.

Advising and Collaborations

While specific student mentorship details are unreported, Dr. Theorell operates within Professor Irani's research ecosystem that trains clinicians and scientists in autoimmune neurology. His work involves cross-institutional collaborations with Karolinska Institutet and likely participates in grant-funded projects through the Nuffield Department of Clinical Neurosciences.